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In larger breed dogs an 18G needle will be better and the blood sample will be obtained much more quickly. 29072014 Demonstration by Dr. Dogs Sniff Out Diabetic Danger Signs Faster Than Medical Test The Times If he already knows shake or high five this will be easy to do. How to draw dog blood . The tail can be gently stroked from the base of the tail toward the tail to encourage blood flow. When collecting the sample from the elbow callus think skin scraping. 26082019 First teach your dog to offer his paw or leg. No more than 1 of the animals body weight in one collection or over a 24 hour period. Attach the needed tubes or syringes to remove the proper volume of blood. Selecting the needle size should be based on the size of the dog and the size of the vein. Typically a 22G needle blue needle works for most blood draws. Veterinarians and vet techs must understand the influence of these factors and consider them when interpreting test results. Lightly pinch and h...